Could Neuronal Ageing be Reversed?

Age rings on a tree stump

Photo: Garry Knight /Flickr/ cc by

  • “NR” means Nicotinamide riboside.
  • “NAD +” means nicotinamide adenine dinucleotide, a derivative of niacin (Vitamin B3).
  • NR, a precursor of NAD +, is integral to cellular respiration.
  • “MuSC” means modulated muscle stem cells
  • Mitochondria is the power generator of a cell.
  • Comparing mitochondrial function between aged mice-stem cells indicate that replenishing NR presence in cells improves MuSC in aged mice.
  • NR decreases muscle senescence through regulation of mitochondrial activity. 
  • Regulation of cellular neural aging and melanocyte stem cells via NR shows increased lifespan in aged mice.
  • Cellular neural aging reversal could mean potential for advancing technology and studies combatting age related diseases such as Alzheimer’s, Parkinson’s and Dementia. 
  • Find out more, at AAAS Science.

Posted 10 years ago