Startling Job of Dopamine in Social Interaction

Photo: Parthiv Haldipur/Flickr

  • ASD stands for 'autism spectrum disorders'
  • DRN for our purposes stands for 'dorsal raphe nucleus'
  • Dopamine, brain messenger molecule associated with memory, learning, movement control
  • Researchers found that nerve cells releasing dopamine were particularly active, with short-term isolated mice
    • Suggesting isolation, DRN is primed, prompting social interaction
  •  Scientists found, when this group of dopamine neurons in DRN was:
    • Stimulated it caused more social interaction
    • Inhibited it caused less interaction
  • Findings also suggest, at least in mice, that:
    • Altered social behavior linked to social rank
    • Social dominant more sensitive by isolation
  • Application: helpful, determining social anxiety or ASD targets
  • Published in the Journal Cell

Posted 10 years ago